Calgary Stampeders vs Saskatchewan Roughriders Prediction – CFL Week 6

Calgary Stampeders vs Saskatchewan Roughriders Prediction - CFL Week 6

The undefeated Saskatchewan Roughriders host the red-hot Calgary Stampeders to start Week 6 of the CFL season. Both teams have won a game and had a bye week over the last two weeks. But only one of them will come out of this week with a victory. Here’s our comprehensive breakdown ahead of this Week 6 showdown, including my Calgary Stampeders vs Saskatchewan Roughriders prediction.

Our Calgary Stampeders vs Saskatchewan Roughriders Pick

  • Pick: Saskatchewan Roughriders −5
  • Confidence: ★★★★☆
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Game Snapshot

  • Matchup: Calgary Stampeders vs Saskatchewan Roughriders
  • Date & Time: Friday, July 11, 2025, 9:00 PM EDT
  • Venue: Mosaic Stadium, Regina
  • Broadcast: TSN / RDS
Odds Spread Moneyline Total
Saskatchewan −5 −230 53
Calgary +5 +190

Key Storylines

Recent Form

  • The Roughriders remain unbeaten at 4‑0. They are allowing under 25 points per game and will look to keep dominating on both sides of the ball here.
  • Calgary is 3‑1 on the season. Their most recent game was an impressive 37–16 win over Winnipeg last week in the “Stampede Bowl”.

Quarterback Play

  • Saskatchewan’s QB Trevor Harris is expected back following injury. He has completed 72.5% of his passes so far this year.
  • Calgary’s Vernon Adams Jr. had two TD passes against Winnipeg last week. He is third in the CFL in passing yards and will look to lead the Stamps to a big win here.

Anticipated Matchup Advantages

  • Saskatchewan has a stingy defense. They are allowing under 25 PPG and could put pressure on Adams to force him into mistakes.
  • Calgary running back Dedrick Mills is second in the CFL in rushing yards. Calgary’s ability to run block could offset the advantage gained from the Saskatchewan pass rush.
  • Saskatchewan is 4-0 straight up and against the spread this season.
  • Calgary is 3-1 straight up and against the spread for the season.
  • Saskatchewan is 3-1 to the over so far this season.
  • The Stampeders are 2-2 on over/unders heading into Week 6.
  • Home/Road splits: Saskatchewan is 2-0 at home, Calgary is 1-0 on the road.

Calgary Stampeders vs Saskatchewan Roughriders Model Projection

Score Projection: Saskatchewan 31 – Calgary 24

Win Probability: Saskatchewan 62%, Calgary 38%

Final Thoughts

Calgary is not an easy team to beat convincingly. And while I don’t think this is a double-digit game, I do think that Saskatchewan will win by a touchdown or so. The Roughriders have been explosive on both sides of the ball. They are good at generating pressure and should make life tough on Vernon Adams Jr. while they make big plays offensively with their starting QB back under center. Expect Saskatchewan to move to 5-0 on the year with a win here.

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