– American Frances Tiafoe is set to compete against Lorenzo Musetti in the quarterfinals of the French Open on Tuesday.
– Tiafoe has not lost a single set in his four matches.
– Discover my predictions and picks for Tiafoe vs Musetti, along with the odds for the French Open quarterfinal.
For the first time since 1996, two American men have reached the French Open quarterfinals. However, sportsbooks aren’t favoring Frances Tiafoe to continue his run. As the 15th seed, Tiafoe is considered an underdog against the 8th seed, Lorenzo Musetti, in their Tuesday match.
The match begins at 8am ET on Court Philippe-Chatrier in Paris, France, with coverage by TBS/truTV/TNT and Max.
**Tiafoe vs Musetti: Picks and Predictions**
– Over 34.5 Games (-125)
Despite previously expressing eagerness for the clay season to end, Tiafoe has dominated his side of the draw, becoming the first American man to reach the quarterfinals since 2003.
Tiafoe’s power was once hindered by the slow clay, but he has made significant improvements this year. He hasn’t dropped a set in his four matches, only facing a tiebreaker once. His latest win was a straight-set triumph over Germany’s Daniel Altmaier, where he excelled at the net.
Now, he faces his toughest challenge yet in Musetti, known for consistency this season. Tiafoe may be the underdog, but his recent form suggests he can challenge Musetti, possibly leading to a long match.
**Tiafoe vs Musetti: Head-to-Head Results**
Musetti has overcome challenges in his last two matches, recovering from a set and break deficit in the third round and winning a tough match against 10th seed Holger Rune in the Round of 16. This gave him his first win over a top-10 player at a Major, extending his strong clay court season.
Musetti reached the Monte-Carlo Final and was a semifinalist in Madrid and Rome, holding an 18-3 record on clay in 2025. He trails Tiafoe 3-2 in their overall matchups; however, Tiafoe has won their last two encounters on grass and hardcourt, with their last clay match going the distance in Rome.
In their Challenger history, Tiafoe leads 4-3, with a 1-2 record on clay. All their clay matches have been close, suggesting at least four sets in this upcoming match, likely surpassing 34.5 games, similar to Musetti’s last two matches at Roland Garros.
**Frances Tiafoe vs Lorenzo Musetti**
The best odds for over 34.5 games is -125 at Caesars. Musetti is the favorite with a -450 moneyline, while Tiafoe is a +350 underdog.
*Musetti lays 6.5 games on the spread, and Tiafoe holds value in this market too. He may be new to this stage at the French Open, but Tiafoe has experience with deep Grand Slam runs, being a two-time US Open semifinalist and Australian Open quarterfinalist. Expect a competitive match with a semifinal spot at stake.*
- SCCG Management. The Gambling Industry’s Global Connector. Access Here.
- Source: SCCGManagement.com
